BIOTINYLATED SURFOME PROFILING IDENTIFIES POTENTIAL BIOMARKERS FOR DIAGNOSIS AND THERAPY OF ASPERGILLUS FUMIGATUS INFECTION

Biotinylated Surfome Profiling Identifies Potential Biomarkers for Diagnosis and Therapy of Aspergillus fumigatus Infection

ABSTRACT Aspergillus fumigatus is one of the most common airborne molds capable of causing mycoses and allergies in humans.During infection, fungal surface proteins mediate the first contact with the human immune system to evade immune responses or to induce hypersensitivity.Several methods have been established for surface proteomics (surfomics).B

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Smarcb1 Loss Results in a Deregulation of esBAF Binding and Impacts the Expression of Neurodevelopmental Genes

The murine esBAF complex plays a major role in the regulation of gene expression during stem cell development and differentiation.As one of its core subunits, Smarcb1 is indispensable for its function and its loss is connected Sinks to neurodevelopmental disorders and participates in the carcinogenesis of entities such as rhabdoid tumours.We explor

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The neurobiology of wellness: 1H-MRS correlates of agency, flexibility and neuroaffective reserves in healthy young adults

Proton magnetic resonance spectroscopy (1H-MRS) is a noninvasive imaging technique that measures the concentration of metabolites in defined areas of the human brain in vivo.The underlying structure of natural metabolism-emotion relationships is unknown.Further, there is a wide range of between-person differences in metabolite concentration in heal

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